General Cell Based Assays

A broad array of cell-based assays designed for use with a variety of live cell experiments and procedures. Ideal for molecular and cell biology research applications.

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3,691 – 3,705 of 6,795 results

3,691

Eurofins Discoverx PathHunter eXpress mCXCR2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0513E2MCP0L)

The PathHunter mCXCR2 (IL8RB) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL8/IL-8) based activation of mCXCR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCXCR2 and EA-tagged β-Arrestin-2. Activation of mCXCR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.

Pricing & Availability

3,692

Eurofins Discoverx PathHunter eXpress IL20RA/IL10RB Dimerization Assay, 10pl Kit. (93-1020E3CP0L)

The PathHunter IL20RA/IL10RB Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-26) induced dimerization of IL20RA/IL10RB receptors. This product uses EFC technology. The cell line included overexpresses IL20RA target protein fused to PK alongside IL10RB target protein fused to EA. Upon ligand-induced dimerization of IL20RA/IL10RB, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.

Pricing & Availability

3,693

Eurofins Discoverx PathHunter eXpress mINSRb Functional Assay, 10-Plate Kit. (93-1017E3CP16L)

The PathHunter eXpress mINSRb Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated mINSRb dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged mINSRb and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of the protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.

Pricing & Availability

3,694

Eurofins Discoverx InCELL Hunter eXpress BTK Kinase Binding Assay, 2pl Kit. (96-0056E15CP0M)

The InCELL Hunter eXpress BTK Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of BTK via detection of BTK levels. This product uses EFC technology. The cell line included overexpresses BTK target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.

Pricing & Availability

3,695

Eurofins Discoverx cAMP Hunter eXpress LHCGR CHO-K1 GPCR Assay, 10-Plate Kit. (95-0106E2CP2L)

The cAMP Hunter LHCGR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. luteinizing hormone) based activation of LHCGR GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type LHCGR, a naturally Gs coupled GPCR. Upon activation of LHCGR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.

Pricing & Availability

3,696

Abcam Overall Exosome Capture and Quantification Assay Kit (Human Serum, Colorimetric).

Overall Exosome Capture and Quantification Assay Kit (Human Serum, Colorimetric).

The product is subject to the following: Abcam Restricted Use Statement

Pricing & Availability

3,697

Eurofins Discoverx PathHunter eXpress PTHR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0315E2CP0M)

The PathHunter PTHR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. PTH) based activation of PTHR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTHR1 and EA-tagged β-Arrestin-2. Activation of PTHR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.

Pricing & Availability

3,698

Eurofins Discoverx cAMP Hunter eXpress AVPR2 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0150E2CP2L)

The cAMP Hunter AVPR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. vasopressin) based activation of AVPR2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type AVPR2, a naturally Gs coupled GPCR. Upon activation of AVPR2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.

Pricing & Availability

3,699

Sino Biological Human IL-1RAcP / IL-1R3 Protein (His Tag), Endotoxin-Free 1mg

A DNA sequence encoding the human IL1R3 (NP_002173.1) extracellular domain (Met 1-Glu 359) was expressed, fused with the a C-terminal polyhistidine tag.